Recombinant Human MYDGF (N-6His) Protein
Produktgrößen
50 µg
£511,00
32-18043-50UG
Über dieses Produkt
- SKU:
- 32-18043
- Zusätzliche Namen:
- UPF0556 protein C19orf10; stromal cell-derived growth factor SF20; C19orf10; Myeloid-derived growth factor; MYDGF
- Weitere Details:
- Molecular weight: 18 KDaDescription: Recombinant Human Myeloid-derived Growth Factor is produced by our E.coli expression system and the target gene encoding Ser33-Leu173 is expressed with a 6His tag at the N-terminus.Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen; prostate and lung; and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-; STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php