Recombinant Human IL-12 Protein
Produktgrößen
50 µg
£854,00
32-18034-50UG
Über dieses Produkt
- SKU:
- 32-18034
- Zusätzliche Namen:
- Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell; IL12A ; NKSF1 stimulatory factor chain 1
- Weitere Details:
- Molecular weight: 22.5and34.7 KDaDescription: Recombinant Human Interleukin-12 is produced by our Mammalian expression system and the target gene encoding Arg23-Ser219andIle23-Ser328 is expressed.IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.Human and mouse IL?12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits; respectively. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor; which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-ÃŽ³) and tumor necrosis factor-alpha (TNF-a) from T cells and natural killer (NK) cells; and reduces IL-4 mediated suppression of IFN-ÃŽ³. T cells that produce IL-12 have a coreceptor; CD30; which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8 cytotoxic T lymphocytes.
- Host:
- HEK293
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php