TFF3 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1760-20UG
Über dieses Produkt
- SKU:
- 32-1760
- Zusätzliche Namen:
- TFF-3||ITF||TFI||HITF||hP1.B||TFF3||Trefoil factor 3||Intestinal trefoil factor.
- Weitere Details:
- Source : Escherichia Coli. TFF-3 Human Recombinant produced in E.Coli is a homodimeric; non-glycosylated; polypeptide chain containing 2 x 59 amino acid chains which includes a 40 amino acid trefoil motif containing 3 conserved interamolecular disulfide bonds and having a total molecular mass of 13.2kDa. TFF-3 Human Recombinant is purified by proprietary chromatographic techniques. Proteins of the TFF family are characterized by obtaining a minimum of 1 copy of the trefoil motif; a 40-amino acid domain that contains 3 conserved disulfides. Trefoil Factors are stable secretory proteins expressed in gastrointestinal mucosa which protect the mucosa from insults; stabilize the mucus layer and affect healing of the epithelium.TFF2 inhibits gastric acid motility & secretion. TFF2 stabilizes glycoproteins in the mucus gel through interactions with carbohydrate side chains. TFF3 induces ciliogenesis and promotes airway epithelial ciliated cell differentiation; relatively through an epidermal growth factor receptor-dependent pathway. TFF3 overexpression is crucial for progression in mouse and human hepatocellular carcinogenesis. TFF-3 is normally expressed in hepatocellular carcinoma and its expression associates with tumor grade.
- Aufreinigung:
- Greater than 97.0% as determined by RP-HPLC and SDS-PAGE analysis.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized TFF3 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution TFF3 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg