mRELM b Recombinant Protein
Produktgrößen
25 µg
£528,00
32-1726-25UG
Über dieses Produkt
- SKU:
- 32-1726
- Zusätzliche Namen:
- Resistin-like beta||RELM beta||Cysteine-rich secreted protein FIZZ2||Colon and small intestine-specific cysteine-rich protein||Cysteine-rich secreted protein A12-alpha-like 1||Colon carcinoma-related gene protein||RELM-b||XCP2||HXCP2.
- Weitere Details:
- Source : Escherichia Coli. Mouse RELM-b Recombinant produced in E.Coli is a monomeric; non-glycosylated; polypeptide chain containing 83 amino acids and having a molecular mass of 8.9kDa. The Mouse RETNLB is purified by proprietary chromatographic techniques. RELM-beta (Resistin-Like Molecule-beta) is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3); RELM-alfa (FIZZ1); RELM-beta (FIZZ2) and RELM-gamma. Only resisistin and RELM-beta were found in humans whereas all four RELM family members were identified in rodents.RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably; stool of germ-free mice displaying sterile intestinal tract does not contain RELM-beta until bacterial colonization takes place after pathogen-free mice entered natural environment. Some; but not all; colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant.The physiological function of RELM-beta is not known. High doses of recombinant RELM-beta showed hyperglycemic effects including lowered glucose disposal and increased hepatic glucose production in mice.
- Aufreinigung:
- Greater than 97% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized RETNLB is stable at -20[o]C. After reconstitution the protein should be kept at all times at -20[o]C. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg