Recombinant Human BAFF-R protein with C-terminal mouse Fc
Produktgrößen
50 µg
£688,00
32-17041-50UG
Über dieses Produkt
- SKU:
- 32-17041
- Zusätzliche Namen:
- BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin
- Weitere Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 33.6 kDa after removal of the signal peptide.The apparent molecular mass of BAFF-R-mFc is approximately 35-55 kDa due to glycosylation. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
- Aufreinigung:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg
