rPrl R Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1691-20UG
Über dieses Produkt
- SKU:
- 32-1691
- Zusätzliche Namen:
- PRL-R||Prolactin receptor||Lactogen receptor||Prlr.
- Weitere Details:
- Source : Escherichia Coli. Prolactin Receptor Rat Extra Celleular Domain Recombinant produced in E.Coli is a non-glycosylated; Polypeptide chain containing 206 amino acids and having a molecular mass of 24120 Dalton. The Prolactin Receptor is purified by proprietary chromatographic techniques. Prolactin is a pituitary hormone involved in the stimulation of milk production; salt and water regulation; growth; development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated; at least in part; by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription. Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation; stimulation of milk; protein synthesis as well as the regulation of numerous reproductive functions. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor; a member of the cytokine receptor family; varies in size (short and long forms) with tissue source and species; from ~40 kDa to 100 kDa. The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site; a single transmembrane domain and a cytoplasmic region; the length of which appears to influence ligand binding and regulate cellular function.
- Aufreinigung:
- Greater than 97.0% as determined by:(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized PRL-R although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Prolactin Receptor should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg