PDGF BB Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1659-10UG
Über dieses Produkt
- SKU:
- 32-1659
- Zusätzliche Namen:
- Glioma-derived growth factor||GDGF||Osteosarcoma-derived Growth Factor||ODGF||SIS||SSV||PDGF2||c-sis||FLJ12858||PDGF-BB||PDGF B-chain||Platelet-derived growth factor beta polypeptide||Becaplermin.
- Weitere Details:
- Source : Escherichia Coli. Platelet-Derived Growth Factor BB Human Recombinant is a homodimeric; non-glycosylated; polypeptide chain containing 2x109 amino acids (218 amino acids in total) and having a molecular mass of 24.3 kDa. PDGF-BB is purified by proprietary chromatographic techniques. PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB); where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7; at sites where this gene and that for COL1A1 are located; are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.
- Aufreinigung:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Platelet-derived Growth Factor BB although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution PDGF BB should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg