OPG Fc Recombinant Protein
Produktgrößen
50 µg
£528,00
32-1639-50UG
Über dieses Produkt
- SKU:
- 32-1639
- Zusätzliche Namen:
- TNFRSF11B||OPG||OCIF||Osteoclastogenesis inhibitory factor||TR1||MGC29565.
- Weitere Details:
- Source : Pichia Pastoris. Recombinant OPG produced in yeast contains 2x412 amino acid residues; including 180 residues from mature OPG (a.a 22-201) and 232 residues from the Fc protein of human IgG1; and has a calculated molecular mass of 109.6kDa. Osteoprotegerin acts as decoy receptor for rankl and thereby neutralizes its function in osteoclastogenesis. OPG inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local rankl/opg ratio. Osteoprotegerin may also play a role in preventing arterial calcification. May act as decoy receptor for trail and protect against apoptosis. Trail binding blocks the inhibition of osteoclastogenesis.
- Aufreinigung:
- Greater than 90.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Osteoprotegerin although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution OCIF should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg