Midkine; His Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1606-20UG
Über dieses Produkt
- SKU:
- 32-1606
- Zusätzliche Namen:
- NEGF-2||Neurite Growth-Promoting Factor 2||MK||Neurite outgrowth-promoting protein||Midgestation and kidney protein||Amphiregulin-associated protein||ARAP||Neurite outgrowth-promoting factor 2||FLJ27379||Midkine||MK1||NEGF2.
- Weitere Details:
- Source : Escherichia Coli. Midkine Human Recombinant is manufactured with N-terminal fusion of His Tag; having a molecular mass of 14.6 kDa protein and containing 121 amino acid residues of the Midkine human and 10 additional amino acid residues - His Tag . Midkine (MK) is the product of a retinoic acid responsive gene; MK; and is a member of a family of heparin binding factors. It contains 121 amino acid residues including 10 conserved cysteine residues; all of which appear to be disulphide linked.Midkine is expressed during embryogenesis; showing an expression pattern that suggests functions in neurogenesis; cell migration; secondary organogenetic induction; and mesoderm-epithelial interaction.The widespread downregulation of MK in the adult human is reverted in a number of cancers; in which polypeptides are able to act as both transforming growth factors and promoters of angiogenesis.Midkine (MK); induces chemotaxis of human neutrophils and was found to trigger mobilization of intracellular calcium of these cells.Midkine induces histamine release from rat peritoneal mast cells with a rapid response in a dose dependent manner.Midkine is also a potent stimulator of collagen and glycosaminoglycan synthesis.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg