Midkine Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1605-20UG
Über dieses Produkt
- SKU:
- 32-1605
- Zusätzliche Namen:
- NEGF-2||Neurite Growth-Promoting Factor 2||MK||Neurite outgrowth-promoting protein||Midgestation and kidney protein||Amphiregulin-associated protein||ARAP||Neurite outgrowth-promoting factor 2||FLJ27379||Midkine||MK1||NEGF2.
- Weitere Details:
- Source : Escherichia Coli. Midkine Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 123 amino acids and having a molecular mass of 13.4kDa. The Midkine is purified by proprietary chromatographic techniques. Midkine (MK) is the product of a retinoic acid responsive gene; MK; and is a member of a family of heparin binding factors. It contains 121 amino acid residues including 10 conserved cysteine residues; all of which appear to be disulphide linked.Midkine is expressed during embryogenesis; showing an expression pattern that suggests functions in neurogenesis; cell migration; secondary organogenetic induction; and mesoderm-epithelial interaction.The widespread downregulation of MK in the adult human is reverted in a number of cancers; in which polypeptides are able to act as both transforming growth factors and promoters of angiogenesis.Midkine (MK); induces chemotaxis of human neutrophils and was found to trigger mobilization of intracellular calcium of these cells.Midkine induces histamine release from rat peritoneal mast cells with a rapid response in a dose dependent manner.Midkine is also a potent stimulator of collagen and glycosaminoglycan synthesis.
- Aufreinigung:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Midkine although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Midkine should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg