MIA Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1602-20UG
Über dieses Produkt
- SKU:
- 32-1602
- Zusätzliche Namen:
- Melanoma-derived growth regulatory protein precursor||Cartilage-derived retinoic acid-sensitive protein||CD-RAP||MIA.
- Weitere Details:
- Source : Escherichia Coli. Melanoma Inhibitory Activity Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain consisting of 108 amino having a total molecular mass of 12237 Dalton.The MIA is purified by proprietary chromatographic techniques. The Melanoma Inhibitory protein (MIA) was identified as an inhibitor of in vitro growth of malignant melanoma cells. The protein contains a SH3 domain. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors; including gliomas; in an autocrine fashion. In a study of human melanoma cell lines with different metastatic capacity MIA mRNA expression appeared to be inversely correlated with pigmentation. MIA has been shown to represent a very sensitive and specific serum marker for systemic malignant melanoma that might be useful for staging of primary melanomas; detection of progression from localized to metastatic disease during follow-up; and monitoring therapy of advanced melanomas.
- Aufreinigung:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized MIA although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution MIA should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg