IL36G 152 a.a. Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1533-10UG
Über dieses Produkt
- SKU:
- 32-1533
- Zusätzliche Namen:
- Interleukin 36 gamma||IL1F9||interleukin 1 family member 9||Interleukin-1 epsilon||IL-1RP2||IL-1H1||IL1E||interleukin 1-related protein 2||Interleukin-1 homolog 1.
- Weitere Details:
- Source : Escherichia Coli. IL36G (152 a.a.) Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 152 amino acids and having a molecular mass of 17.0kDa.The IL36G (152 a.a.) is purified by proprietary chromatographic techniques. IL-36gamma belongs to the IL-1 family which includes IL-1b; IL-1a; IL-1ra; IL-18; IL-36 Ra (IL-1F5); IL-36a (IL-1F6); IL-36b (IL-1F8); IL-37 (IL-1F7) and IL-1F10. ). The IL-1 family members display a 12 b-strand; b-trefoil configuration; and are thought to have ascended from a mutual ancestral gene. IL-36g is an 18-22 kDa; 169aa intracellular and secreted protein which holds no signal sequence; no prosegment and no potential N-linked glycosylation sites. Human IL-36g shares 58%- 69% aa sequence homology with mouse; rat; bovine and equine IL-36g; and 23 - 57% aa sequence homology with other family members. The IL-36g receptor is a mixture of IL-1 Rrp2; mostly located in epithelia and keratinocytes; and the extensively expressed IL-1 RAcP. All IL-36 (a; b and g) activate N F-B and MAPK pathways in an IL-1 Rrp2 dependent reaction. Additionally; IL-36g induces production of inflammatory cytokines and chemokines like CXCL8/IL-8.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized IL36g Human although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution IL36g should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg