IL 31 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1511-10UG
Über dieses Produkt
- SKU:
- 32-1511
- Zusätzliche Namen:
- Interleukin 31||IL31||IL-31.
- Weitere Details:
- Source : Escherichia Coli. IL-31 human recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 141 amino acids (24-164 a.a.) and having a molecular mass of 15.8 kDa. IL-31 produced by activated Th2-type T cells; cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is continuesly expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases; such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connectd with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes part as a proinflammatory cytokine derived from Th2 cells.Serum IL-31 level is higher in patients with atopic dermatitis. IL-31 is involved in a broad range of immune- & non-immune cells & possesses potential pleiotropic physiological functions; including regulating hematopoiesis & immune response; causing inflammatory bowel disease; airway hypersensitivity & dermatitis.
- Aufreinigung:
- Greater than 95.0% as determined by(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized IL-31 Recombinant although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution IL-31 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg