IL 28A Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1503-20UG
Über dieses Produkt
- SKU:
- 32-1503
- Zusätzliche Namen:
- Interleukin-28A||IL-28A||IFN-Lambda 2||Interferon-Lambda 2||Cytokine ZCYTO20||IL28A||IFNL2||ZCYTO20.
- Weitere Details:
- Source : Escherichia Coli. IL-28A human recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 175 amino acids and having a molecular mass of 19.6 kDa. IL-28A is distantly related to type I interferons and the IL-10 family. Expression of IL-28A is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor; beta (IL10RB) and interleukin 28 receptor; alpha. IL-28A exhibits common features with type I IFNs such as antiviral activity; antiproliferative activity and in vivo antitumour activity.IL-28A acts similarly to IFNs; but is less effective generally and has activity in a more limited range of cell lines. IFN-ambda 1; IFN-lambda 2 and IFN-lambda 3 are closely positioned genes on human chromosome 19.IL-28A induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells; in an IFN-gamma-independent manner. IL-28A is able to generate tolerogenic DCs; an activity that could thwart IFN-beta functions. IL-28A produced in response to viral infection; activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection.
- Aufreinigung:
- Greater than 85% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized IFN-Lambda 2 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution IFN-Lambda 2 Recombinant should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg