IL 17F Recombinant Protein
Produktgrößen
25 µg
£528,00
32-1471-25UG
Über dieses Produkt
- SKU:
- 32-1471
- Zusätzliche Namen:
- Cytokine ML-1||IL-17F||Interleukin-17F precursor||IL17F||ML1||ML-1.
- Weitere Details:
- Source : Escherichia Coli. Interleukin-17F Human Recombinant produced in E.Coli is a homodimeric; cysteine linked; non-glycosylated polypeptide chain containing 2 x 134 amino acids and having a total molecular mass of 30.1 kDa.The IL-17F Human is purified by proprietary chromatographic techniques. IL-17F having an accession number of Q96PD4 is a cytokine that shares sequence similarity with IL17. IL-17F is expressed by activated T cells; and has been shown to stimulate the production of several other cytokines; including IL6; IL8; and CSF2/GM_CSF. IL-17F inhibits the angiogenesis of endothelial cells and induce endothelial cells to produce IL2; TGFB1/TGFB; and monocyte chemoattractant protein-1. IL-17F induces stromal cells to produce proinflammatory and hematopoietic cytokines. Intestinal IL17F gene expression is increased in active CD.IL-17A & IL-17F alleles influence the susceptibility to and pathophysiological features of ulcerative colitis independently. IL-17F and MIF gene polymorphisms are significantly associated with the development of functional dyspepsia. The initiation of IL-17F/IL-17R signaling pathway requires the receptor ubiquitination by TRAF6. IL-17F induces expression of IFN-gamma-inducible protein 10 (IP-10) by activating Raf1-mitogen-activated protein kinase 1/2-extracellular-regulated kinase 1/2-p90 ribosomal S6 kinase-cyclic AMP response element-binding protein signaling pathway.
- Aufreinigung:
- Greater than 97.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Interleukin Human IL17F although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Human IL-17F should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg