IL 15 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1455-10UG
Über dieses Produkt
- SKU:
- 32-1455
- Zusätzliche Namen:
- IL-15||MGC9721.
- Weitere Details:
- Source : Escherichia Coli. Interleukin-15 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 114 amino acids (and an N-terminal Methionine) and having a molecular mass of 12.8kDa. The IL-15 is purified by proprietary chromatographic techniques. The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits; and may compete for the same receptor; and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases; as well as the phosphorylation and activation of transcription activators STAT3; STAT5; and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L); possibly through the transcription activation activity of STAT6; and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
- Aufreinigung:
- Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Interleukin-15 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution IL15 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg