IL 13 Variant Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1448-10UG
Über dieses Produkt
- SKU:
- 32-1448
- Zusätzliche Namen:
- Interleukin-13||NC30||ALRH||BHR1||P600||IL-13||MGC116786||MGC116788||MGC116789.
- Weitere Details:
- Source : Escherichia Coli. Interleukin-13 Variant Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 114 amino acids; with a substitution of Q for R at position 112 compared with the wild type IL-13; having a molecular mass of 12.5 kDa. The IL-13 Variant is purified by proprietary chromatographic techniques. IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression; and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity; thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene; IL3; IL5; IL4; and CSF2 form a cytokine gene cluster on chromosome 5q; with this gene particularly close to IL4.
- Aufreinigung:
- Greater than 95% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Interleukin-13 Variant although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution IL13 Variant should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg