SARS MERS RBD
Produktgrößen
2 µg
£452,00
32-13821-2UG
10 µg
£528,00
32-13821-10UG
Über dieses Produkt
- SKU:
- 32-13821
- Zusätzliche Namen:
- Middle East respiratory syndrome coronavirus; Human betacoronavirus 2c EMC/2012; MERS-CoV; MERS; MERSCoV RBD; MERS RBD; receptor binding domain; RBD; Spike RBD protein; Spike glycoprotein; S glycoprotein; E2; Peplomer protein
- Weitere Details:
- Source:Sf9; Baculovirus cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivitynullSince April 2012; cases of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been identified in various countries. Coronaviruses are the cause of the common cold; SARS (severe acute respiratory syndrome) and other severe illnesses with high mortality rates; all are classified into coronavirus family. MERS-CoV is a new type of SARS found in the coronavirus family causing severe pneumonia with sudden and serious respiratory illness with high mortality rates as well. Since January 27th 2015; the WHO has reported 956 human cases; including 351 deaths. More cases of the new coronavirus strain are expected. Like in other coronaviruses; large surface spike glycoprotein is a central structural protein of this virus; it is located above the virion surface to bind and enter into the target cell. Spike protein has 2 domains- S1 and S2. The S1 domain is responsible for cellular tropism and interaction with target cell; while the S2 domain is responsible for membrane fusion. The C-terminal of S1 domain contains a receptor binding domain; and is also a potential target for vaccine development and an antigen for diagnosis.SARS MERS RBD Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 258 amino acids (358-606 aa) and having a molecular mass of 28.2kDa.SARS MERS RBD is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
- Format:
- The SARS MERS RBD solution (0.5mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php