ULBP3 Human; Sf9
Produktgrößen
2 µg
£452,00
32-13809-2UG
10 µg
£528,00
32-13809-10UG
Über dieses Produkt
- SKU:
- 32-13809
- Zusätzliche Namen:
- UL16 Binding Protein 3; Retinoic Acid Early Transcript 1N; ALCAN-Gamma; NKG2DL3; N2DL-3; RAET1N; UL16-Binding Protein 3; NKG2D Ligand 3; N2DL3; ULBP3
- Weitere Details:
- Source:Sf9; Baculovirus cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivitynullUL16 Binding Protein 3 (ULBP3) is a ligand for the NKG2D receptor in NK cells. ULBPs activate different signaling pathways resulting in the production of cytokines and chemokines. ULBP3 is a ligand for the KLRK1/NKG2D receptor; along with at least ULBP1 and ULBP2. Binding of ULBPs ligands to KLRK1/NKG2D stimulates calcium mobilization and activation of the JAK2; STAT5; ERK and PI3K kinase/Akt signal transduction pathway. ULBP3 has lower affinity for KLRK1/NKG2D compared to ULBP1 and ULBP2 and stimulates weaker signaling responses than does ULBP2 or ULBP1.ULBP3 Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 430 amino acids (30-217a.a) and having a molecular mass of 49.3kDa.ULBP3 is fused to a 239 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.
- Format:
- The ULBP3 solution (1mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php