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SOST Mouse

Produktgrößen
2 µg
£452,00
32-13801-2UG
10 µg
£528,00
32-13801-10UG
Über dieses Produkt
SKU:
32-13801
Zusätzliche Namen:
SOST; Sclerostin; 5430411E23Rik.
Weitere Details:
Source:HEK293 cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivitynullSclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein antagonists. Sclerostin functions as a negative regulator of bone growth; by inhibiting bone formation. SOST is expressed mainly in the bone; cartilage; kidney; liver; bone marrow and primary osteoblasts differentiated for 21 days. SOST gene defects cause sclerosteosis and bone dysplasia.SOST Mouse Recombinant produced in HEK293 cells is a single; glycosylated polypeptide chain (24-211 a.a) containing 194 amino acids and having a molecular mass of 21.9 kDa.SOST is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Format:
SOST protein (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
Aufreinigung:
Greater than 90.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules