SELPLG Human
Produktgrößen
5 µg
£458,00
32-13794-5UG
20 µg
£548,00
32-13794-20UG
Über dieses Produkt
- SKU:
- 32-13794
- Zusätzliche Namen:
- Cutaneous Lymphocyte-Associated Associated Antigen; Selectin P Ligand; PSGL-1; CD162 Antigen; P-Selectin Glycoprotein Ligand 1; CLA.
- Weitere Details:
- Source:HEK293 Cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivitynullSELPLG glycoprotein functions as a high affinity counter-receptor for the cell adhesion selectin molecules (P; E and L) located in stimulated T lymphocytes and myeloid cells. SELPLG binds leukocytes to activated platelets or endothelia expressing selectins; a vital role in leukocyte trafficking throughout inflammation. In order to have a high-affinity binding activity SELPLG needs two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans. Polymorphisms and abnormal expression of SELPLG are linked to defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.SELPLG Human Recombinant produced in HEK293 Cells is a single; glycosylated polypeptide chain containing 496 amino acids (42-295 a.a) and having a molecular mass of 53.4kDa.SELPLG is fused to a 239 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.
- Format:
- The SELPLG solution (1mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php