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LILRB1 Human

Produktgrößen
2 µg
£452,00
32-13778-2UG
10 µg
£528,00
32-13778-10UG
Über dieses Produkt
SKU:
32-13778
Zusätzliche Namen:
Leukocyte immunoglobulin-like receptor subfamily B member 1;Leukocyte immunoglobulin-like receptor 1; leucocyte Ig-like receptor B1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; myeloid inhibitory receptor 7; Monocyte/macrophage immunoglobulin-like receptor 7; Ig-like transcr
Weitere Details:
Source:Sf9; Baculovirus cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivityBiological activity is > 50%. It is defined by the ability of the immobilized protein to support the adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells; while the cells are added to LILRB1 coated plates at 5ug/ml.Leukocyte Immunoglobulin Like Receptor B1 (LILRB1) is a member of the leukocyteimmunoglobulinlike receptor (LIR) family. LILRB1is expressed on immune cells; binds to MHC classI molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immuneresponse. LILRB1 controls inflammatory responses and cytotoxicity to help focus the immune responseand limit autoreactivity. LILRB1 is also expressed on the surface of B cells and monocytes; subsets of NKcells; gamma d T cells;memory/effector CD8+ T cells and monocyte-derived dendritic cells.LILRB1 Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 446 amino acids (24-461 a.a) and having a molecular mass of 48.5kDa.LILRB1 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Format:
The LILRB1 solution (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
Aufreinigung:
Greater than 95.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules