CFH Rat
Produktgrößen
10 µg
£727,00
32-13753-10UG
50 µg
£1353,00
32-13753-50UG
Über dieses Produkt
- SKU:
- 32-13753
- Zusätzliche Namen:
- Complement factor H; H factor 1; CFH; HF; HF1; HF2.
- Weitere Details:
- Source:Rat Plasma.Physical Appearance:Sterile filtered solution.Biological ActivitynullComplement factor H (CFH) is an important regulatory component of the alternative pathway of complement. CFH is prevents complement activation on host cells and tissues; mainly the kidney. CFH controls the formation and decay of the alternative pathway C3/C5 convertase and acts as a cofactor for factor I which proteolytically inactivates C3b when C3b is bound to factor H. The N-terminal 5 domains of CFH bind to C3b and inhibit binding of factor B thus reducing the formation of C3/C5 convertase. CFH also binds to preformed C3/C5 convertases and causes quick release of the catalytic subunit Bb. These activities are necessary for controlling the spontaneous activation of the alternative pathway amplification process in plasma. In addition; CFH controls the formation and decay of these enzymes when C3b is attached to the surface of particles.Rat Complement Factor H produced in Rat plasma having a total molecular mass of 155kDa.
- Format:
- CFH protein solution contains phosphate Buffered Saline; pH 7.2.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- CFH Rat is stable at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen below -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php