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C7 Human

Produktgrößen
20 µg
£600,00
32-13736-20UG
100 µg
£1030,00
32-13736-100UG
Über dieses Produkt
SKU:
32-13736
Zusätzliche Namen:
Complement component C7; C7.
Weitere Details:
Source:Human Plasma.Physical Appearance:Sterile filtered solution.Biological ActivitynullC7 is necessary for formation of the membrane attack complex and is activated by bindingat the cell membrane to recently-formed C5b;C6 complexes. Each pathway of complement activation generates proteolytic enzyme complexes which bind the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing C5a and activating C5b. Although C5b is unstable it remains bound to the activating complex for a few minutes during which it binds a single C6 from the surrounding fluid or it decays and is no longer capable of forming MAC. The C5b;6 complex may also remain connected to the C3/C5 convertase where the binding of a single C7 exposes a membrane-binding region and C5b;6;7 can enter into the bilipid layer of the target cell.Human Complement C7 produced in Human plasma having a molecular mass of 92.4kDa.
Format:
C7 protein solution contains 10mM Sodium phosphate and 145mM NaCl; pH 7.3.
Aufreinigung:
Greater than 90.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
C7 Human is stable at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen below -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules