FAP Human
Produktgrößen
2 µg
£452,00
32-13689-2UG
10 µg
£528,00
32-13689-10UG
Über dieses Produkt
- SKU:
- 32-13689
- Zusätzliche Namen:
- Prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; Dipeptidyl peptidase FAP; Fibroblast activation protein alpha; FAPalpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; Serine integral membrane protease; Surface-expressed prot
- Weitere Details:
- Source:Sf9; Baculovirus cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivitySpecific activity > 5;000 pmol/min/ug. It is defined by the amount of enzyme that hydrolyzes 1.0 pmole of ZGP-AMC per minute at pH 7.5; at 37°C.DPP4 also called adenosine deaminase complexing protein-2; and T-cell activation antigen CD26 is a serine exopeptidase and complex enzyme that is expressed on the surface of most cell types. DPPIV is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. DPP4 plays a role in t-cell activation. DPP4 is associated with intracellular signal transduction; apoptosis and involved in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors; chemokines; neuro peptides. Furthermore; DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and GLP-1.FAP Human produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 744 amino acids (26-760aa) and having a molecular mass of 86.1 kDa.FAP is fused to a 6 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.
- Format:
- The FAP solution (0.25mg/ml) contains 20% Glycerol and Phosphate-Buffered Saline (pH 7.4).
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php