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ENPP2 Human

Produktgrößen
2 µg
£452,00
32-13687-2UG
10 µg
£528,00
32-13687-10UG
Über dieses Produkt
SKU:
32-13687
Zusätzliche Namen:
ENPP2; ATX; PDNP2; ATX-X; NPP2; PD-IALPHA; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 2; ectonucleotide pyrophosphatase/phosphodiesterase 2; ENPP2; E-NPP 2; AUTOTAXIN; Extracellular lysophospholipase D; LysoPLD.
Weitere Details:
Source:HEK293 Cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivitySpecific activity is greater than 15;000 units/mg; and defined as the amount of enzyme that hydrolyze 1nmole of bis (pNitrophenyl) phosphate per minute at pH8.7 at 37?.Ectonucleotide Pyrophosphatase-2; aka ENPP2; a part of the ectonucleotide pyrophosphatasefamily. ENPP2 is able to cut the phosphodiester bond between the alpha and the beta position of triphosphate nucleotides; acting as an ectonucleotide phosphodiesterase producing pyrophosphate; as most members of the ENPP family. It is unlike ENPP-1 and ENPP-3; has weak activity against nucleotides; but shows a lysophospholipase D activity which allows the formation of LPA and choline from lysophosphatidylcholine. As well; ENPP-2 and LPA are involved in several inflammatory-driven diseases such as arthritis and asthma.ENPP2 Human Recombinant produced in HEK293 Cells is a single; glycosylated polypeptide chain containing 825 amino acids (49-863a.a) and having a molecular mass of 94.9kDa.ENPP2 is fused to a 6 amino acid His-tag at C-terminus; and is purified by proprietary chromatographic techniques.
Format:
The ENPP2 solution (0.25mg/ml) contains PBS (pH7.4) and 10% glycerol.
Aufreinigung:
Greater than 90.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules