C1R Human
Produktgrößen
20 µg
£583,00
32-13681-20UG
100 µg
£1030,00
32-13681-100UG
Über dieses Produkt
- SKU:
- 32-13681
- Zusätzliche Namen:
- Complement C1r subcomponent; Complement component 1 subcomponent r; C1R.
- Weitere Details:
- Source:Human Plasma.Physical Appearance:Sterile Filtered solution.Biological ActivitynullC1r enzyme is the activated form of C1r proenzyme which is inactive zymogen until C1 is activated.C1r is a subunit of the C1 complex which is the first complement component in the classical pathway of complement. C1 is a non-covalent calcium-dependent complex containing1 C1q; 2 C1r and 2 C1s molecules.Each C1q bindsthe Fc domains of IgG or IgM by using2 or more of its six arms. The binding of multiple arms to immune complexes causesthe production of 2 proteases that cleave and activate the 2 C1s protease zymogens in the complex by the C1r proteins. The activation of C1r results from cleavage of C1r into 2 fragments of 57;000 and 35;000 Dalton.Human Complement C1r produced in Human plasma having a molecular mass of 92 kDa.
- Format:
- 140mM NaCl; 10mM Imidazole and 2mM EDTA; pH 7.4.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Human C1r is stable at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen below -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php