MCP1 Human; HEK
Produktgrößen
2 µg
£452,00
32-13676-2UG
10 µg
£528,00
32-13676-10UG
Über dieses Produkt
- SKU:
- 32-13676
- Zusätzliche Namen:
- CCL2; C-C motif chemokine 2; GDCF-2; HSMCR30; JE; HC11; MCAF; MCP-1; MCP1; Scya2; Sigje; SMC-CF; Immediate-early serum-responsive protein JE; Monocyte chemoattractant protein 1; Small-inducible cytokine A2.
- Weitere Details:
- Source:HEK293 Cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivityMeasured its ability to chemoattract using THP-1 human acute monocytic leukemia cells. The ED50 range = 30 ng/ml.Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone; CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor ?B (NF?B).CCL2 recruits immune cells; such as monocytes; to sites of tissue injury and infection.This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide; with a molecular weight of approximately 13kDa. As with many other CC chemokines; CCL2 is located on chromosome 17 in humans.The cell surface receptors that bind CCL2 are CCR2 and CCR5MCP1 Human HEK Recombinant produced in HEK293 Cells is a single; glycosylated polypeptide chain containing 82 amino acids (24-99a.a) and having a molecular mass of 9.5 kDa.MCP1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Format:
- The MCP1 solution (0.25mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php