VEGF Equine
Produktgrößen
10 µg
£512,00
32-13672-10UG
50 µg
£870,00
32-13672-50UG
Über dieses Produkt
- SKU:
- 32-13672
- Zusätzliche Namen:
- VEGF-A; VPF; glioma-derived endothelial cell mitogen.
- Weitere Details:
- Source:Escherichia Coli.Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.Biological ActivityThe ED50 as determined by HUVEC Proliferation is = 10 ng/mL; corresponding to a specific activity of = 1.0 x 10^5 units/mg.Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies; VEGF activity has been mostly studied on cells of the vascular endothelium; although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration; neurons; cancer cells; kidney epithelial cells ).VEGF mediates increased vascular permeability; induces angiogenesis; vasculogenesis and endothelial cell growth; promotes cell migration; and inhibits apoptosis. In vitro; VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein is linked to POEMS syndrome; also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.VEGF Equine Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 2 x 165 amino acids and having a total molecular mass of 38.6 kDa.The VEGF is purified by proprietary chromatographic techniques.
- Format:
- Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM Sodium Phosphate; pH 7.5.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized VEGF although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution VEGF Human should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php