IL5 Mouse; Sf9
Produktgrößen
2 µg
£452,00
32-13652-2UG
10 µg
£528,00
32-13652-10UG
Über dieses Produkt
- SKU:
- 32-13652
- Zusätzliche Namen:
- interleukin 5; Il; Il-5; B-cell growth factor II; BCGF-II; Cytotoxic T-lymphocyte inducer; Eosinophil differentiation factor; T-cell replacing factor; EDF; TRF; B cell differentiation factor I; IL5.
- Weitere Details:
- Source:Sf9; Baculovirus cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivityMeasured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range = 1 ng/ml.The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5is a main regulator of eosinopoiesis; eosinophil maturation and activation. The elevated production of IL5is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL5is a heterodimer; whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL5; together with those for interleukin 4 (IL4); interleukin 13 (IL13); and CSF2; form a cytokine gene cluster on chromosome 5. IL5; IL4; and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.IL5 Mouse produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 119 amino acids (21-133 a.a) and having a molecular mass of 13.9kDa.IL5 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Format:
- The IL5 solution (0.25mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php