IL1A Canine
Produktgrößen
2 µg
£452,00
32-13649-2UG
10 µg
£528,00
32-13649-10UG
Über dieses Produkt
- SKU:
- 32-13649
- Zusätzliche Namen:
- interleukin 1 alpha; IL1A; interleukin-1 alpha precursor;BAF; Hematopoietin-1; IL1 alpha; IL1F1hematopoietin-1; LAF; LEM; preinterleukin 1 alpha; pro-interleukin-1-alpha.
- Weitere Details:
- Source:Sf9; Baculovirus cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivityMeasured in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 range = 2 ng/ml.The cytokine IL-1 alpha or hematopoietin 1 is a member to the interleukin 1 family; encoded by the IL1A gene in humans. Essentially Il-1 is in charge of inflammation and the rising of fever and sepsis. In order to disturb the mentioned processes and treatment for diseases; inhibitors for Interleukin 1 alpha are being developed. Neutrophils and macrophages are the main activators of IL-1 alpha; as well as endothelial and epithelial cells. By binding to the il1 receptor it is a major part in the immune response regulation. In the activation process of tumor necrosis factor-alpha the IL1A has a part as well; and has physiological; metabolic and hematopoietic activities.IL1A Canine produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 166 amino acids (109-265 aa) and having a molecular mass of 19.3 kDa.IL1A is fused to a 6 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.
- Format:
- IL1A protein solution (0.25mg/ml) containing Phosphate-Buffered Saline (pH7.4) and 10% glycerol.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php