CNTF Rat; His
Produktgrößen
2 µg
£452,00
32-13643-2UG
10 µg
£528,00
32-13643-10UG
Über dieses Produkt
- SKU:
- 32-13643
- Zusätzliche Namen:
- Ciliary neurotrophic factor; CNTF; Cntf.
- Weitere Details:
- Source:Escherichia Coli.Physical Appearance:Sterile filtered colorless solution.Biological ActivitynullCNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene; which results in aberrant splicing; leads to ciliary neurotrophic factor deficiency; but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus; the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.CNTF Rat Recombinant produced in E. coli is a single; non-glycosylated polypeptide chain containing 223 amino acids (1-200a.a) and having a molecular mass of 25.2kDa.CNTF is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Format:
- CNTF protein solution (0.5mg/ml) containing phosphate buffered saline (pH 7.4) and 10% glycerol.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php