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Antikörper

HERV-K

Produktgrößen
100 µg
£547,00
32-13633-100UG
0.5 mg
£1030,00
32-13633-0.5MG
Über dieses Produkt
SKU:
32-13633
Zusätzliche Namen:
HERVK is related with several tumors such as passenger virus; and anti-Retroviral therapy against amyotrophic lateral sclerosis/ALS has exhibited to decrease the symptoms of amyotrophic lateral sclerosis/ALS. High counts of viral sequences exist in the human genome but stay silent. Though; in patho
Weitere Details:
Source: Escherichia Coli.Sterile Filtered clear solution.HERVK is related with several tumors such as passenger virus; and anti-Retroviral therapy against amyotrophic lateral sclerosis/ALS has exhibited to decrease the symptoms of amyotrophic lateral sclerosis/ALS. High counts of viral sequences exist in the human genome but stay silent. Though; in pathological conditions; these viruses are produced. Human Endogenous Retrovirus-K; is produced in neurons of a subpopulation of patients with amyotrophic lateral sclerosis/ALS; a progressive neurodegenerative disease. The envelope protein of this HERV results in degeneration of neurons; and transgenic animals producing this protein advance an ALS-like syndrome triggered by nucleolar dysfunction in motor neurons. Reactivation of the HERVK is controlled by the transcription factor TDP-43. Therefore; therapeutic tactics against this virus alter the course of the disease.The E.Coli derived HERV-K recombinant truncated protein is fused to a Six histidine tag at C-terminus and has a MW of 51.5kDa (pI 9.06).
Aufreinigung:
Protein is >90% pure as determined by SDS PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
HERV-K although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody