IGFBP7 His Recombinant Protein
Produktgrößen
10µg
£528,00
32-1355-10UG
Über dieses Produkt
- SKU:
- 32-1355
- Zusätzliche Namen:
- Insulin-like growth factor-binding protein 7||IBP-7||IGF-binding protein 7||IGFBP-7||IGFBP-rP1||MAC25 protein||PGI2-stimulating factor||Prostacyclin-stimulating factor||Tumor-derived adhesion factor||TAF||IGFBP7||MAC25||PSF||AGM||FSTL2||RAMSVPS||IGFB
- Weitere Details:
- Source : Escherichia Coli. IGFBP7 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 279 amino acids (27-282 a.a.) and having a molecular mass of 28.8kDa.IGFBP7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Insulin-like Growth Factor-Binding Protein 7 (IGFBP7) is a member of the IGFBP family. IGFBP family members are all cysteine rich proteins with conserved cysteine and have an IGFBP domain; a Kazal-like domain and an Ig-like C2-type domain. IGFBP7 is expressed in a broad range of normal human tissues and it mostly shows reduced expression in cancer cell lines of prostate; breast; colon; and lung origin. IGFBP7 has a role in skeletal myogenesis by binding to IGF in a manner which inhibits IGF induced differentiation of skeletal myoblasts; without disturbing IGF induced proliferation. Moreover; IGFBP7 suppresses growth and colony formation of prostate and breast cancer cell lines via an IGF independent mechanism; which triggers a delay in the G1 phase of the cell cycle; and increased apoptosis.
- Aufreinigung:
- Greater than 85% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg