SIGLEC10 Human
Produktgrößen
2 µg
£452,00
32-13425-2UG
10 µg
£528,00
32-13425-10UG
Über dieses Produkt
- SKU:
- 32-13425
- Zusätzliche Namen:
- SIGLEC10; PRO940; SLG2; SIGLEC-10; Sialic acid-binding Ig-like lectin 10 isoform 3; Siglec-like protein 2.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Sialic Acid Binding Ig Like Lectin 10(SIGLEC10) is a part of the immunoglobulin superfamily that is expressed on eosinophils; B cells; monocytes and neutrophils. SIGLEC10 is an adhesion molecule that mediates sialic-acid dependent binding to cells.SIGLEC10 is a ligand for CD52; the target of the therapeutic monoclonal antibody Alemtuzumab. Also; it binds to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24.This binding is modulated by cis interactions of SIGLEC10 with sialated molecules on the same cell.SIGLEC10 Human produced in Sf9 Insect cells is a single; glycosylated polypeptide chain containing 678 amino acids (17-455 a.a.) and having a molecular mass of 75.6kDa. SIGLEC10 is expressed with a 239 hIgG-His-tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php