SFRP4 Human; sf9
Produktgrößen
1 µg
£452,00
32-13414-1UG
5 µg
£528,00
32-13414-5UG
Über dieses Produkt
- SKU:
- 32-13414
- Zusätzliche Namen:
- Secreted Frizzled Related Protein 4; Secreted Frizzled-Related Protein 4; Frizzled Protein; Human Endometrium; SFRP-4; FRPHE Secreted Frizzled-Related Protein 4; Secreted Frizzled-Related Protein 4; FRP-4; PYL; SFRP4; FRPHE.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Secreted frizzled-related protein 4 (SFRP4) belongs to the SFRP family which contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs serve as soluble modulators of Wnt signaling. SFRP4 may serve as a regulator of adult uterine morphology and function. SFRP4 increases apoptosis during ovulation possibly via modulation of FZ1/FZ4/WNT4 signaling. SFRP4 also has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. SFRP4 is expressed in proliferative endometrium and several types of ovarian; endometrial and Brest tumors. SFRP4 is expressed in mesenchymal cells and in cardiomyocytes. SFRP4 expression in ventricular myocardium correlates with apoptosis related gene expression. SFRP4 is up-regulated in failing myocardium.SFRP4 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 337 amino acids (19-346 a.a.) and having a molecular mass of 38.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). SFRP4 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php