RLN3 Human
Produktgrößen
5 µg
£452,00
32-13387-5UG
25 µg
£528,00
32-13387-25UG
Über dieses Produkt
- SKU:
- 32-13387
- Zusätzliche Namen:
- Relaxin 3; Prorelaxin H3; RXN3; Insl7; ZINS4; H3; Relaxin 3 (H3); Relaxin-3; RLN3.
- Weitere Details:
- Source: Escherichia Coli.Sterile Filtered White lyophilized (freeze-dried) powder.Relaxin-3 (RLN3) belongs to the relaxin family. Relaxins are endocrine and autocrine/paracrine hormones. Relaxin; which is produced by the ovary; targets the mammalian reproductive system to ripen the cervix; elongate the pubic symphysis and inhibit uterine contraction. Unlike human Relaxins 1 and 2; Relaxin 3 does not seem to have a role in reproduction; however it is involved in stress response in the brain stem. RLN3 is the only known ligand for the G-protein-coupled receptor GPCR135; titled RXFP3. In addition; RLN3 binds the LGR7 (RXFP1) receptor; however with lower affinity than Relaxin-2. Even though binding of RLN3 to LGR7 increases intracellular cAMP; binding to GPCR135 suppresses cAMP accumulation; indicating coupling to Gi; Go; or Gz by this receptor.Relaxin-3 Human Recombinant produced in E.Coli is a disulfide-linked heterodimeric; non-glycosylated; polypeptide chain containing 24 amino acids for A chain and 27 amino acids for B chain and having a molecular mass of 2.5kDa for A chain and 3kDa for B chain.The Relaxin-3 is purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized RLN3 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Relaxin-3 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php