NFATC2 Human
Produktgrößen
1 µg
£452,00
32-13335-1UG
5 µg
£528,00
32-13335-5UG
Über dieses Produkt
- SKU:
- 32-13335
- Zusätzliche Namen:
- Nuclear Factor Of Activated T Cells 2; Nuclear Factor Of Activated T-Cells; Cytoplasmic; Calcineurin-Dependent 2; Nuclear Factor Of Activated T-Cells 2; NFAT Pre-Existing Subunit; NF-ATc2; NFAT1; NFATP; Nuclear Factor Of Activated T-Cells; Preexisting Component ; Nuclear Factor Of Activated T-Cell
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.NFATC2; also known as nuclear factor of activated T-cells 2; belongs to the nuclear factor of activated T cells family. NFATC2 takes a significant part in the course of T helper cell differentiation; activation; and effector function. Even though KO of an individual NFAT isoform in T cells directs to rather minor effects; T cells lacking for NFATC1 and 2 totally fail to produce T helper cell effector cytokines; for instance the interleukins IL-4 and IL-2. Moreover; NFATC2 is highly phosphorylated and kept in the cytoplasm. Next T cell receptor stimulation; dephosphorylation via calcium-activated calcineurin induces a conformational modification of NFATC2 which reveals a few nuclear localization sequences.NFATC2 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 290 amino acids (396-678a.a.) and having a molecular mass of 33.1kDa. (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). NFATC2 is expressed with a 7 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php