MYBPC3 Human
Produktgrößen
2 µg
£452,00
32-13328-2UG
10 µg
£528,00
32-13328-10UG
Über dieses Produkt
- SKU:
- 32-13328
- Zusätzliche Namen:
- Myosin Binding Protein C Cardiac; C-Protein Cardiac Muscle Isoform; Myosin-Binding Protein C Cardiac; Cardiac MyBP-C; CMD1MM; LVNC10; MYBP-C; CMH4; FHC; MYBPC3.
- Weitere Details:
- Source: Escherichia Coli.Filtered White lyophilized (freeze-dried) powder.Myosin Binding Protein C; Cardiac (MYBPC3) is the cardiac isoform of myosin-binding protein C expressed exclusively in heart muscle. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase upon adrenergic stimulation may be associated with modulation of cardiac contraction. MYBPC3 gene mutations are one of the causes of familial hypertrophic cardiomyopathy. In vitro MYBPC3 binds MHC; F-actin and native thin filaments; and modifies the activity of actin-activated myosin ATPase. MYBPC3 may modulate muscle contraction or it may have a more structural role.MYBPC3 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain (Met1-Phe271) containing 281 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 29.6kDa.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php