LZTFL1 Human
Produktgrößen
5 µg
£452,00
32-13308-5UG
20 µg
£528,00
32-13308-20UG
Über dieses Produkt
- SKU:
- 32-13308
- Zusätzliche Namen:
- Leucine Zipper Transcription Factor-Like 1; BBS17; Leucine Zipper Transcription Factor-Like Protein 1; Leucine zipper transcription factor-like protein 1.
- Weitere Details:
- Source: Escherichia Coli.Sterile filtered colorless solution.Leucine Zipper Transcription Factor-Like 1; also known as LZTFL1 is a ubiquitously expressed protein which localizes to the cytoplasm. LZTFL1 interacts with Bardet-Biedl Syndrome proteins (BBS) and during its interaction with BBS protein complexes; regulates protein trafficking to the ciliary membrane. Nonsense mutations in LZTFL1 cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized partly by polydactyly; obesity; cognitive impairment; hypogonadism; and kidney failure. LZTFL1 also acts as a tumor suppressor; possibly by interacting with E-cadherin as well as the actin cytoskeleton and in this manner regulating the transition of epithelial cells to mesenchymal cells.LZTFL1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 322 amino acids (1-299 a.a) and having a molecular mass of 37.0kDa.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php