LBP Human; HEK
Produktgrößen
2 µg
£452,00
32-13292-2UG
10 µg
£528,00
32-13292-10UG
Über dieses Produkt
- SKU:
- 32-13292
- Zusätzliche Namen:
- Lipopolysaccharide-binding protein; LBP; MGC22233; Ly88.
- Weitere Details:
- Source: HEK293 Cells.Filtered White lyophilized (freeze-dried) powder.Lipopolysaccharides (LPS) are a type of glycolipids on the outer cell wall of Gram-negative bacteria. Lipopolysaccharide binding protein (aka LBP) is a plasma protein which facilitates the diffusion of bacterial LPS (endotoxin). LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. In cooperation with bactericidal permeability-increasing protein (BPI); LBP binds LPS and interacts with the CD14 receptor; most likely playing a role in regulating LPS-dependent monocyte responses. LBP belongs to a family of structurally and functionally related proteins; including BPI; plasma cholesteryl ester transfer protein (CETP); and phospholipid transfer protein (PLTP). The LBP gene is found on chromosome 20; directly downstream of the BPI gene. LBP catalyzes the transfer of LPS monomers from LPS aggregates to HDL particles; to phospholipid bilayers; and to a binding site on soluble CD14 (sCD14). sCD14 is capable of speeding up the transfer by receiving an LPS monomer from an LPS aggregate; and then yielding it to an HDL particle; therefore acting as a soluble "shuttle" for an insoluble lipid.LBP Human Recombinant is a single; glycosylated polypeptide chain containing 462 amino acids (26-481a.a) and having a molecular mass of 51.7kDa (calculated). LBP is fused to a 6 a.a His tag at C-terminal.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php