KIR2DL4 Human
Produktgrößen
1 µg
£452,00
32-13278-1UG
5 µg
£528,00
32-13278-5UG
Über dieses Produkt
- SKU:
- 32-13278
- Zusätzliche Namen:
- Killer Cell Immunoglobulin Like Receptor; Two Ig Domains And Long Cytoplasmic Tail 4;Killer Cell Immunoglobulin-Like Receptor; Two Domains; Long Cytoplasmic Tail 4;Killer Cell Inhibitory Receptor 103AS; MHC Class I NK Cell Receptor KIR103AS;CD158 Antigen-Like Family Member D; KIR-103AS; KIR103AS; C
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Killer cell immunoglobulin-like receptor 2DL4; also known as KIR2DL4 is part of the killer cell Ig-like receptor (KIR) family. KIR proteins with the long cytoplasmic domain transduce inhibitory signals through an immune tyrosine-based inhibitory motif (ITIM); whereas KIR proteins which contain the short cytoplasmic domain; lack the ITIM motif and as a substitute associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. KIR2DL4 stimulates NK cells to produce IFN-gamma and stimulation with IL-2 upregulates cell surface expression on CD56dimcells and leads to the inhibition of the cytolytic NK cell function.KIR2DL4 Human Recombinant produced in Sf9 Insect cells is a single; glycosylated polypeptide chain containing 458 amino acids (24-242 a.a.) and having a molecular mass of 51kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). KIR2DL4 is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php