JMJD6 Human
Produktgrößen
2 µg
£452,00
32-13275-2UG
10 µg
£528,00
32-13275-10UG
Über dieses Produkt
- SKU:
- 32-13275
- Zusätzliche Namen:
- Jumonji Domain Containing 6; Phosphatidylserine Receptor; Jumonji Domain-Containing Protein 6; Histone Arginine Demethylase JMJD6; Peptide-Lysine 5-Dioxygenase JMJD6; JmjC Domain-Containing Protein 6; Lysyl-Hydroxylase JMJD6; PTDSR; PSR; Bifunctional Arginine Demethylase And Lysyl-Hydroxylase JMJD6
- Weitere Details:
- Source: Escherichia Coli.Sterile filtered colorless solution.Jumonji Domain Containing 6; also known as JMJD6 performs as a lysyl-hydroxylase which catalyzes 5-hydroxylation on specific lysine residues of target proteins for instance U2AF2/U2AF65 and LUC7L2; as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65; affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Additionally to peptidyl-lysine 5-dioxygenase activity; JMJD6 performs as an RNA hydroxylase; as proposed by its ability to bind single strand RNA. Furthermore; it acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) as well as histone H4 at 'Arg-3' (H4R3me); thus taking a part in histone code.JMJD6 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 437 amino acids (1-414 a.a) and having a molecular mass of 50.0kDa.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php