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Antikörper

HLA-G Human

Produktgrößen
2 µg
£452,00
32-13260-2UG
10 µg
£528,00
32-13260-10UG
Über dieses Produkt
SKU:
32-13260
Zusätzliche Namen:
Major Histocompatibility Complex; Class I; G; HLA-G Histocompatibility Antigen; Class I; G; MHC Class I Antigen G; B2 Microglobulin; HLA G Antigen; HLA Class I Histocompatibility Antigen; Alpha Chain G; Mutant MHC Class Ib Antigen; Mutant MHC Class I Antigen; MHC Class Ib Antigen; HLA-6.0; MHC-G; H
Weitere Details:
Source: Escherichia Coli.Sterile Filtered clear solution.HLA-G (Major Histocompatibility Complex Class I G) is a member of the HLA class I heavy chain paralogues. This class I molecule is a heterodimer which comprises a heavy chain as well as a light chain; beta-2 microglobulin; while the heavy chain is fixed in the membrane. HLA-G is expressed on fetal derived placental cells. HLA-G is a non-classical class-I HLA molecule linked with immuno-modulatory & anti-inflammatory properties which interacts with inhibitory receptors such as; ILT2/ILT4/KIR2DL4; that are present on different immune cells. HLA-G inhibits the proliferation of T cells; B cells & natural killer cells; moreover it also induces regulatory T cells.HLA-G Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 309 amino acids (25-308 a.a) and having a molecular mass of 35.3kDa.HLA-G is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Aufreinigung:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody