GPNMB Human; Sf9
Produktgrößen
2 µg
£452,00
32-13251-2UG
10 µg
£528,00
32-13251-10UG
Über dieses Produkt
- SKU:
- 32-13251
- Zusätzliche Namen:
- Transmembrane glycoprotein NMB; Transmembrane glycoprotein HGFIN; GPNMB; HGFIN; NMB; Glycoprotein (transmembrane) nmb.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Glycoprotein Nmb (GPNMB) is a member of the PMEL/NMB family. GPNMB is a type I transmembrane glycoprotein which exhibits homology to the pMEL17 precursor; a melanocyte-specific protein. GPNMB is expressed in the lowly metastatic human melanoma cell lines and xenografts but has no expression in the highly metastatic cell lines. GPNMB might be involved in growth delay and reduction of metastatic potential. GPNMB is up-regulated in a number of cancer cells; including in glioblastoma multiforme. GPNMB is expressed in many melanoma cells; as well as in tissue macrophages; including liver Kuppfer cells and lung alveolar macrophages; in podocytes and in some cells of the ciliary body of the eye (at protein level). GPNMB is hardly detectable in the healthy brain.GPNMB Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 462 amino acids (22-474a.a.) and having a molecular mass of 51.8kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).GPNMB is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php