FGG Human
Produktgrößen
2 µg
£452,00
32-13233-2UG
10 µg
£528,00
32-13233-10UG
Über dieses Produkt
- SKU:
- 32-13233
- Zusätzliche Namen:
- Fibrinogen gamma chain isoform gamma-A; Fibrinogen gamma chain; PRO2061.
- Weitere Details:
- Source: Escherichia Coli.Sterile Filtered clear solution.Fibrinogen gamma chain isoform gamma-A (FGG) is the gamma component of fibrinogen; which is a blood-borne glycoprotein; comprised of 3 pairs of nonidentical polypeptide chains. FGG along with fibrinogen alpha (FGA) and fibrinogen beta (FGB) polymerizes to form an insoluble fibrin matrix. Following vascular injury; FGG is cleaved by thrombin to create fibrin; which is the most abundant component of blood clots. FGG functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Moreover; different cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading; exhibit vasoconstrictor and chemotactic activities; and are mitogens for a number of cell types. Maternal fibrinogen is vital for successful pregnancy. FGG gene mutations lead to some disorders; including dysfibrinogenemia; hypofibrinogenemia and thrombophilia. Fibrin accumulation is also linked with infection; where it protects against IFNG-mediated hemorrhage.FGG Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 434 amino acids (27-437 a.a) and having a molecular mass of 48.9kDa.FGG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php