FCGR3A Human; Sf9
Produktgrößen
2 µg
£452,00
32-13228-2UG
10 µg
£528,00
32-13228-10UG
Über dieses Produkt
- SKU:
- 32-13228
- Zusätzliche Namen:
- Low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma; RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD16a; FCGR3A; FCG3; FCGR3; IGFR3; CD16; FCGRIII.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile filtered colorless solution.Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A) is a receptor for the Fc portion of immunoglobulin G; and is involved in the elimination of antigen-antibody complexes from the circulation; as well as other antibody-dependent responses. FCGR3A needs to associate with the gamma subunit of Fc epsilon. The FCGR3A receptor is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide; while FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. In addition; FCGR3A is expressed on macrophages; subpopulation of T-cells; immature thymocytes and placental trophoblasts. FCGR3A mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses; such as phagocytosis. FCGR3A gene mutations are linked with susceptibility to recurrent viral infections; susceptibility to systemic lupus erythematosus; and alloimmune neonatal neutropenia.FCGR3A Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 200 amino acids (18-208 a.a.) and having a molecular mass of 22.8kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).FCGR3A is fused with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php