CEA Human; His
Produktgrößen
2 µg
£452,00
32-13141-2UG
10 µg
£528,00
32-13141-10UG
Über dieses Produkt
- SKU:
- 32-13141
- Zusätzliche Namen:
- Carcinoembryonic Antigen Related Cell Adhesion Molecule 5; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5; Meconium Antigen 100; CEA; Carcinoembryonic Antigen; CD66e Antigen; CD66e; Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA.
- Weitere Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Carcinoembryonic antigen (CEA) is a glycoprotein present in fetal digestive-tract tissues; it’s involved in cell adhesion. The production of CEA stops before birth. CEA is called tumor marker since its elevated levels are found in the serum from individuals with colorectal; gastric; pancreatic; lung and breast carcinomas and in heavy smokers.There are also benign conditions that elevate CEA levels such as smoking; infection; inflammatory bowel disease; pancreatitis; cirrhosis of the liver; and some benign tumors (in the equivalent organs which have cancers with elevated CEA). Typically; higher levels of CEA are found in men; smokers; and older individuals.The presence of CEA assists in screening; in evaluating recurrent or disseminated disease; and in determining the success of surgical removal of malignant tumors.CEA levels can be used as indicators of treatment success. The normal values range from 0.0 to 2.5 ng/ml of serum (from blood); in non-smokers; a greater amount than that may be suggestive of cancer. Levels above 20 ng/ml before treatment are associated with cancer which has already metastasized. Benign conditions do not usually cause a CEA increase over 10 ng/ml. The high levels of CEA should return to normal after successful therapy; however if during follow up there’s an elevation in CEA levels it indicates a recurrence of tumor.Carcinoembryonic antigen family belongs to the immunoglobulin superfamily; it consists of 29 genes; 18 of which are normally expressed.CEA Human Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 659 amino acids (35-685a.a.) and having a molecular mass of 72.3kDa (Molecular size on SDS-PAGE will appear at approximately 70-150kDa). CEA is expressed with an 8 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php