B.Microti IRA
Produktgrößen
50µg
£1062,00
32-13048-50UG
100µg
£1353,00
32-13048-100UG
Über dieses Produkt
- SKU:
- 32-13048
- Weitere Details:
- Source: Sf9 insect cells. Sterile Filtered clear solution. Babesiosis is a disease caused by apicomplexan parasites of the Babesia genus. The Babesia microti life cycle involves 2 hosts; which include a rodent; mainly the white-footed mouse (Peromyscus leucopus) and a tick in the Ixodes genus. During a blood meal; a Babesia-infected tick introduces sporozoites into the mouse host. Sporozoites pass into the erythrocytes and undergo asexual reproduction (budding). In the blood; some parasites differentiate into male and female gametes; though these cannot be distinguished by light microscopy. The definitive host is the tick. Once ingested by an proper tick; gametes unite and undergo a sporogonic cycle resulting in sporozoites. Transovarial transmission (aka vertical or hereditary transmission) has been detected for large" Babesia species but not for the "small" Babesia; such as B. microti. Humans enter the cycle when bitten by the infected ticks. Thus during a blood meal; a Babesia-infected tick introduces sporozoites into the human host. Sporozoites then enter erythrocytes and undergo asexual replication (budding). Multiplication of the blood-stage parasites is responsible for the clinical manifestations of the disease. Humans typically are dead-end hosts. However; human-to-human transmission is well acknowledged to occur via contaminated blood transfusions.Recombinant Babesia Microti IRA produced in SF9 is a glycosylated; polypeptide chain having a calculated molecular mass of 77;554 Dalton. B.Microti IRA is expressed with a 10xHis tag at N-terminus and purified by proprietary chromatographic techniques."
- Aufreinigung:
- Greater than 80.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php