GDNF Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1237-10UG
Über dieses Produkt
- SKU:
- 32-1237
- Zusätzliche Namen:
- ATF1||ATF2||HFB1-GDNF||GDNF.
- Weitere Details:
- Source : Escherichia Coli. Glial derived Neurotrophic Factor Human Recombinant produced in E.Coli is a homodimer; non-glycosylated; polypeptide chain containing 2 x 135 amino acids and having a total molecular mass of 30;360 Dalton. GDNF is purified by proprietary chromatographic techniques. GDNF promotes the survival and differentiation of dopaminergic neurons in culture; and is able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF; two additional alternative transcripts encoding distinct proteins; referred to as astrocyte-derived trophic factors; have also been described. Mutations in this gene may be associated with Hirschsprung disease.GDNF enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
- Aufreinigung:
- Greater than 98.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Glial-derived Neurotrophic Factor although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution GDNF should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg